Exposure by inhalation results in the fastest appearance of toxic symptoms, followed by the oral route and finally the dermal route. Diagnostic determination of organophosphate poisoning is often accomplished by confirming reduced acetylcholinesterase (AChE) activity in blood or brain. The cholinergic syndrome is caused by … OPs have replaced the banned organochlorine compounds and are a major cause of animal poisoning. Acute Organophosphate poisoning This is the syndrome recognised by doctors and Poisons Units. Symptoms occur within 24 hours of exposure and include collapse, breathing problems, sweating, diarrhoea, vomiting, excessive salivation, heart dysrrhythmias, extreme anxiety … Signs and symptoms of organophosphate poisoning can be divided into three broad categories: (1) muscarinic effects, (2) nicotinic effects, and (3) central nervous system (CNS) effects. The organophosphates (OPs) are derivatives of phosphoric or phosphonic acid. OP poisoning can occur in a variety of situations and can be accidental or suicidal. Sick dogs have a depressed immunity system and exposure to any insecticide can affect them greatly. Organophosphate Poisoning. Nerve Agent and Organophosphate Pesticide Poisoning. Presentation is highly variable due to differences in dose, agent toxicity, and type of exposure. 2-PAM (1 to 2 g in adults; 20 to 40 mg/kg in children) is given over 15 to 30 minutes IV after exposure to an organophosphate or carbamate because, frequently, whether the poison is an organophosphate or carbamate is unknown at the time of treatment. It is common in developing countries. Symptoms of Organophosphate Poisoning. Poisoning can occur due to occupational or accidental exposure, deliberate ingestion, or chemical warfare with nerve gases. Patients exposed to high quantities of these chemicals can develop a variety of symptoms and … Before using any product containing organophosphate on any sick dog, consult a veterinarian. Pralidoxime (2-PAM) is given after atropine to relieve neuromuscular symptoms. The following is a list of possible symptoms of organophosphate poisoning. Symptoms of acute organophosphate poisoning develop during or after exposure, within minutes to hours, depending on method of exposure. Organophosphate poisoning is a neurological syndrome caused by exposure to organophosphate chemicals like those found in insecticides, herbicides, and some nerve agents. Signs and symptoms are not listed in order of presentation or specificity. The following is a more comprehensive list of signs and symptoms that may be encountered in a person exposed to a nerve agent or OP pesticide. All signs and symptoms are cholinergic in nature and affect They vary greatly in toxicity, residue levels, and excretion. 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